These preparations are made from blood donors who have antibodies to a
wide variety of diseases to which they have been exposed. They are used
to protect individuals where a lack or low level of antibody may cause
frequent infections. Normal immunoglobulin is available as an intramuscular
injection or as an intravenous infusion. These preparations can only be
obtained with a doctor’s prescription. Discuss with your doctor
why it has been prescribed for you and the benefits and risks of this
The intramuscular preparation is used for patients who need replacement
of some antibodies of the normal immune system to prevent infections.
It can also be used to prevent infection by the measles and hepatitis
Intravenous normal immunoglobulin
An intravenous preparation is used to prevent infections in patients who
are unable to make their own antibodies. This may be due to a genetic
disorder, chemotherapy or other disease. Intravenous immunoglobulin is
also a relatively new treatment for some auto-immune diseases where the
body’s own immune system becomes overactive and causes a disease.